Function of SSA subfamily of Hsp70 within and across species varies widely in complementing Saccharomyces cerevisiae cell growth and prion propagation.
BACKGROUND:The cytosol of most eukaryotic cells contains multiple highly conserved Hsp70 orthologs that differ mainly by their spatio-temporal expression patterns.Hsp70s play essential roles in protein folding, transport or degradation, and are major players of cellular quality control processes.However, while several reports suggest Quick Start Ov